During this workshop, we will present an end-to-end federated data analysis use case covering federated data discovery and access, bioinformatics analysis, and ethical and legal considerations for responsible and fair data sharing flow. The workshop will comprise a mix of lectures and demos with some hands-on tutorials if time permits. Lectures will introduce key concepts for federated data sharing and analysis, GA4GH Beacon API, GA4GH Passports and Visas, and the Data Use Ontology (DUO), followed by practical sessions on real-world research and clinical applications.

The CINECA webinar series continues with a presentation by Dr Melanie Courtot, from the Ontario Institute for Cancer Research (OICR).

The ability to integrate and harmonise diverse, large human cohort data at scale promises exciting research perspectives and applications. This webinar provides a high-level introduction to some current standards for data representation and access, and tools leveraging them. Finally, we explore how modular assembly of tools and standards enables deployment of Findable, Accessible, Interoperable and Reusable (FAIR) data and showcase applications that “bring it all together”.

The Beacon is a protocol for sharing information about the presence or absence of a specific mutation in a given dataset. The latest version (v2) of the Beacon also allows to: filter by variables or interest (e.g. gender or age), trigger the data access process, and consult clinical annotation about the variants found, among others.

At the end of this training session, participants will be familiarized with Beacon queries, using the UI as well as the API. This training session is part of the CINECA GA4GH Beacon series.

The Beacon v2 Reference Implementation (B2RI) is a free open source Linux-based software created by the Centre for Genomic Regulation (Barcelona, Spain) that allows lighting up a Beacon v2 out-of-the-box.In this training session, a B2RI developer will give an overview on how to use the software to “beaconize” your data (from the user’s perspective).

At the end of this training session, participants will be familiarized with the input and output requirements of the B2RI, as well as with the type of queries allowed. This training session is part of the CINECA GA4GH Beacon series.

The Beacon is a protocol for sharing information about the presence or absence of a specific mutation in a given dataset. The latest version (v2) of the Beacon also allows to: filter by variables or interest (e.g. gender or age), trigger the data access process, and consult clinical annotation about the variants found, among others.

At the end of the training session, participants should have the tools to get started with the implementation autonomously, and have identified the resource persons to answer their questions during the implementation process. This training session is part of the CINECA GA4GH Beacon series.

The Beacon is a protocol for sharing information about the presence or absence of a specific mutation in a given dataset. The latest version (v2) of the Beacon also allows to: filter by variables or interest (e.g. gender or age), trigger the data access process, and consult clinical annotation about the variants found, among others.

In this webinar, the Beacon team at CRG will introduce you to the Beacon v2, its features, address security considerations, and illustrate a few use cases. This webinar is part of the CINECA GA4GH Beacon series.

The training consists of one hour of presentations, followed by a hands-on exercise with a Virtual Machine. In the hand-on part the trainees integrate their VM to ELIXIR AAI as an OpenID Connect client to retrieve a GA4GH Passport. The client then presents the Passport to a Data API to authorise the API call and to stream a dataset. The VMs are available for the trainees for two weeks after the training.

This webinar will focus on how the CINECA project is applying FAIR (Findable, Accessible, Interoperable, Reusable) principles in practice. Enabling federated data discovery, data access, and research and analysis, by using open standards across the federated network, is crucial in order to fully exploit the potential of human cohorts to drive personalised medicine. CINECA is working in collaboration with other GA4GH driver projects developing and implementing the methods and infrastructure which will allow effective use of widely-dispersed data to improve the size and quality of datasets available for disease research.